Weekly Chest CasesCases by Disease Category

Case No : 1163 Date 2020-02-17

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  • Courtesy of Hwayoung Song, Junghoon Kim, Jihang Kim, Kyung Hee Lee, Kyung Won Lee / Seoul National University Bundang Hospital
  • Age/Sex 39 / M
  • Chief ComplaintFever, dyspnea / AML, s/p allogeneic stem cell transplantation (16 months ago)
  • Figure 1
  • Figure 2
  • Figure 3

Diagnosis With Brief Discussion

Diagnosis
Bronchiolitis obliterans syndrome due to chronic graft versus host disease
Radiologic Findings
Fig 1-2. CT scan reveals multiple peribronchial tiny nodules, bronchial wall thickening and minimal bronchiectasis in both lungs. Fig 3. worsening of bronchial dilatation and bronchial wall thickening after 3 months.
Brief Review
Bronchiolitis obliterans, or obliterative bronchiolitis, is the most common and most relevant late noninfectious pulmonary complication after HSCT. Its reported incidence varies from 2% to 48%, likely because of a lack of uniform classification. Most cases manifest within 6
Please refer to
Case 289, Case 617, Case 709,
References
1. Pena E, Souza CA, Escuissato DL, et al. Noninfectious pulmonary complications after hematopoietic stem cell transplantation: practical approach to imaging diagnosis. Radiographics 2014; 34: 663
Keywords
lung, airway, graft versus host disease, bronchiolitis obliterans,

No. of Applicants : 74

▶ Correct Answer : 41/74,  55.4%
  • - Saitama-Sekishinkai Hosptal , Japan MIHOKO YAMAZAKI
  • - Kinki University Faculty of Medicine, , Japan MITSURU MATSUKI
  • - Showa University Fujigaoka Hospital , Japan KYOKO NAGAI
  • - Niigata University , Japan ATSUSHI UEHARA
  • - Mayo Clinic , United States AKITOSHI INOUE
  • - , Korea (South) HYEYOUNG CHOI
  • - McGill University Health Center , Canada Alexandre Semionov
  • - IRSA LA ROCHELLE , France JEAN LUC BIGOT
  • - , Egypt KHALED ABDULGAWAD BORAEE
  • - , Korea (South) CHOHEE KIM
  • - Vita Hospital , Brazil DIOGO LAGO PINHEIRO
  • - Inje University Pusan Paik Hospital , Korea (South) DA SOM KIM
  • - Oita University, Faculty of Medicine , Japan Fumito Okada
  • - University of Michigan , United States GABIN YUN
  • - Other , Korea (South) HONG SANG HYUP
  • - National Center for Global Health and Medicine , Japan MASATOSHI HOTTA
  • - Gifu University Hospital , Japan Yo Kaneko
  • - Seoul National University Hospital , Korea (South) JI HEE KANG
  • - Soonchunhyang University Hospital Bucheon , Korea (South) SEONGHWAN BYUN
  • - Diskapi Yildirim Beyazit Hospital, Ankara , Turkey MERIC TUZUN
  • - Hallym University Dongtan Medical Center , Korea (South) MINSU KIM
  • - , India SUSHANT JOSHI
  • - University of Tsukuba, Dept of Radiology , Japan MANABU MINAMI
  • - , Japan NAOMI YUASA
  • - Ajou University Hospital , Korea (South) HYERIN KIM
  • - Seoul National University Hospital , Korea (South) SE WOO KIM
  • - Asan Medical Center , Korea (South) JIHOON KIM
  • - Kitano hospital , Japan SATOSHI IKEDA
  • - , India SAURABH MAHESHWARI
  • - University of Tsukuba Hospital , Japan SODAI HOSHIAI
  • - , India SHYJUMON GEORGE
  • - Toranomon Hospital , Japan KAORU SUMIDA
  • - Ichinomiya Nishi Hospital , Japan Takao Kiguchi
  • - , Japan KAZUMA TERAUCHI
  • - Private sector , Greece VASILIOS TZILAS
  • - Hamamatsu University Hospital , Japan YUKI HAYASHI
  • - Diagnose.me (BV) / Royal Perth Hospital , Australia YURANGA WEERAKKODY
  • - Chonnam National University Hwasun Hospital , Korea (South) WONGI JEONG
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
  • - Ajou University Hospital , Korea (South) YONG HO JANG
  • - Jiangsu province hospital , China WANGJIAN ZHA
▶ Correct Answer as Differential Diagnosis : 8/74,  10.8%
  • - , Saudi Arabia ALAAELDIN MOHAMED
  • - CH de la Cote Basque , France PAUL ARDILOUZE
  • - NIMS, HYDERABAD , India BHASKAR K
  • - Hamamatsu University Hospital , Japan HAYATO NOZAWA
  • - Medicheck health care , Korea (South) Chae hun Lim
  • - TB centre kasaragod. , India rikhy krishnan
  • - Nishida Hospital , Japan SHOJI OKUDA
  • - National Center for Global Health and Medicine , Japan HIROSHI TAKUMIDA
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